World No 1 Brooks Koepka, who has finished second, first and second in the year’s Majors, joins South Africa’s No 1 Louis Oosthuizen and India’s Shubhankar Sharma for the first two rounds.
The trio are off at 1:04pm as Oosthuizen, who won the event in 2010, headlines the local charge that was bolstered by Dylan Frittelli after his win at the John Deere Classic.
Portrush native Graeme McDowell is off at 9:14am in the company of 2016 winner Henrik Stenson and American Xander Schauffele, who finished joint second at Carnoustie Golf Links last year.
Defending champion Francesco Molinari is looking for his second Major and he tees off alongside American Bryson DeChambeau and and Australia’s Adam Scott at 9:58am.
European Tour members Patrick Reed and Matt Wallace have been paired with 15-time Major winner Tiger Woods and that group get their campaign started at 3:10pm, 11 minutes before Spaniard Jon Rahm and Americans Patrick Cantlay and Matt Kuchar.
Rory McIlroy – who set the course record of 61 at Portrush as a 16-year-old – will get his quest for a fifth Major title started at 10:09am alongside US Open champion Gary Woodland and England’s Paul Casey.
First-round tee-off times All times BST, (a) denotes amateurs
06:35 Charley Hoffman (US), Darren Clarke (NI), James Sugrue (a) (Ire)
06:46 Emiliano Grillo (Arg), Sung Kang (Kor), Thomas Thurloway (a) (Eng)
06:57 Andy Sullivan (Eng), Christiaan Bezuidenhout (SA), Alexander Levy (Fra)
07:08 Zander Lombard (SA), Chan Kim (US), Brandon Wu (a) (US)
07:19 Richard Sterne (SA), Romain Langasque (Fra), Matthias Schmid (a) (Ger)
07:30 Matthew Fitzpatrick (Eng), Padraig Harrington (Irl), Andrew Putnam (US)
07:41 Eddie Pepperell (Eng), Bubba Watson (US), Rafael Cabrera-Bello (Spa)
07:52 Phil Mickelson (US), Shane Lowry (Ire), Branden Grace (SA)
08:03 Mike Lorenzo-Vera (Fra), Alex Noren (Swe), Sam Locke (Sco)
08:14 Webb Simpson (US), Sergio Garcia (Spa), Cheng-Tsung Pan (Tpe)
08:25 Ryan Palmer (US), Andrea Pavan (Ita), Dylan Frittelli (SA)
08:36 Kyle Stanley (US), Robert Macintyre (Sco), Andrew Johnston (Eng)
08:47 Mikko Korhonen (Fin), Oliver Wilson (Eng), Curtis Knipes (a) (Eng)
09:03 Sungjae Im (Kor), Ian Poulter (Eng), Kiradech Aphibarnrat (Tha)
09:14 Henrik Stenson (Swe), Xander Schauffele (US), Graeme McDowell (NI)
09:25 Haotong Li (Chn), Russell Knox (Sco), Bernd Wiesberger (Aut)
09:36 Connor Syme (Sco), Jason Kokrak (US), Austin Connelly (Can)
09:47 Zach Johnson (US), David Duval (US), Corey Conners (Can)
09:58 Bryson DeChambeau (US), Francesco Molinari (Ita), Adam Scott (Aus)
10:09 Gary Woodland (US), Rory McIlroy (NI), Paul Casey (Eng)
10:20 Rickie Fowler (US), Kevin Kisner (US), Hideki Matsuyama (Jpn)
10:31 Si Woo Kim (Kor), Jim Furyk (US), Jimmy Walker (US)
10:42 Luke List (US), Alexander Bjork (Swe), Paul Waring (Eng)
10:53 Shugo Imahira (Jpn), Nate Lashley (US), Benjamin Hebert (Fra)
11:04 Mikumu Horikawa (Jpn), Callum Shinkwin (Eng), Garrick Porteous (Eng)
11:15 Matthew Baldwin (Eng), Prom Meesawat (Tha), Jack Senior (Eng)
11:36 Joaquin Niemann (Chi), Tom Lehman (US), Miguel Angel Jimenez (Spa)
11:47 Byeong-Hun An (Kor), Jorge Campillo (Spa), Chris Wood (Eng)
11:58 Joel Dahmen (US), Adri Arnaus (Spa), Dimitrios Papadatos (Aus)
12:09 Rory Sabbatini (Svk), Stewart Cink (US), Inn-choon Hwang (Kor)
12:20 Erik Van Rooyen (SA), Kurt Kitayama (US), Jake McLeod (Aus)
12:31 Shaun Norris (SA), Ryan Fox (NZ), Dong-kyu Jang (Kor)
12:42 Keith Mitchell (US), Tyrrell Hatton (Eng), Thomas Pieters (Bel)
12:53 Justin Thomas (US), Tommy Fleetwood (Eng), Thorbjorn Olesen (Den)
13:04 Louis Oosthuizen (SA), Brooks Koepka (US), Shubhankar Sharma (Ind)
13:15 Billy Horschel (US), Jazz Janewattananond (Tha), Aaron Wise (US)
13:26 Jordan Spieth (US), Marc Leishman (Aus), Danny Willett (Eng)
13:37 Cameron Smith (Aus), Adam Hadwin (Can), David Lipsky (US)
13:48 Chez Reavie (US), Paul Lawrie (Sco), Justin Harding (SA)
14:04 Tom Lewis (Eng), Takumi Kanaya (a) (Jpn), Brandon Stone (SA)
14:15 Lucas Glover (US), Joost Luiten (Ned), Nino Bertasio (Ita)
14:26 J.B. Holmes (US), Ernie Els (SA), Abraham Ancer (Mex)
14:37 Brandt Snedeker (US), Lee Westwood (Eng), Brian Harman (US)
14:48 Justin Rose (Eng), Tony Finau (US), Lucas Bjerregaard (Den)
14:59 Dustin Johnson (US), Jason Day (Aus), Keegan Bradley (US)
15:10 Tiger Woods (US), Matt Wallace (Eng), Patrick Reed (US)
15:21 Patrick Cantlay (US), Jon Rahm (Spa), Matt Kuchar (US)
15:32 Kevin Streelman (US), Doc Redman (US), Robert Rock (Eng)
15:43 Yuta Ikeda (Jpn), Adrian Otaegui (Spa), Isidro Benitez (Mex)
15:54 Patton Kizzire (US), Sang Hyun Park (Kor), Yuki Inamori (Jpn)
16:05 Yoshinori Fujimoto (Jpn), Doyeob Mun (Kor), Andrew Wilson (Eng)
16:16 Gunn Charoenkul (Tha), Yosuke Asaji (Jpn), Ashton Turner (Eng)